Fumagilin-B combats Nosema, a debilitating disease of adult honey bees similar to dsyentary. The active ingredient Bcyclohexylammonium Fumagilin (Fumagilin-B) is the only compound completely effective against Nosema without harming colonies. Mixing rate is 5.1 grams of Fumagilin-B powder per gallon of heavy (2:1) sugar syrup. The 24 gram bottle will yield approximately 5 gallons of syrup which will treat 2-3 colonies depending on their size and configuration. Complete mixing and dosing instructions are included with each bottle.